TRPC6 and metabolic syndrome: But, TRPC6 immunostaining density was much stronger in the medial layer of MetS pigs as compared to that in the Lean and MetS-SN medial layers, with the TRPC6 staining ratios of adventitia/medial being as follows: Lean 1.13 ± 0.08 (n = 6) vs. MetS 1.56 ± 0.09 (n = 9), and MetS vs. MetS-SN 1.19 ± 0.11 (n = 6).