CNTNAP2 and encephalitis: First, due to the lack of availability of maternal samples and need for large volumes of the injected material, we used IgG from two patients with CASPR2 encephalitis rather than IgG from mothers of children with neurodevelopmental disorders; it is possible that the CASPR2-antibodies in the two patients target different epitopes to those found in the mothers’ samples we previously examined [8].