Furthermore, we also compared allelic and genotypic frequencies of CXCL9 rs10336, CXCL10 rs3921 and CXCL11 rs4619915 polymorphism between HCV-infected patients and healthy people (IBS), and no significant differences were found, indicating that our cohort did not have any significant bias regarding the distribution of CXCL9-11 polymorphisms. The gene discussed is CXCL10; the disease is irritable bowel syndrome.