Genes enriched in these 5 pathways are ER, HER3, MCM2, MCM5, CDT1, CCND3, CDKN2A, RANGAP1, AURKA, HSPB1, GAPDH. Genes such as ER and HER3 reflect the proliferative property of breast cancer cells. The gene discussed is MCM5; the disease is breast cancer.