Also included were 7 DE annotated lncRNAs; HOTAIRM1, DANCR, GAS5, LINC-PINT, RMRP, HEIH, TUG1 and 3 DE novel lincRNAs; TCONS_00041961, TCONS_00295657, TCONS_00298577, which co-located with DE protein-coding genes in XLA patients compared to the healthy subjects. The gene discussed is GAS5; the disease is Bruton-type agammaglobulinemia.