We also detected low expression of MTOR and overexpression of multiple components of mitochondrial complexes I (NDUF; NADH: Ubiquinone Oxidoreductase), III (UQCR; Ubiquinol-Cytochrome C Reductase), IV (COX; Cytochrome C Oxidase) and V (ATP; Adenosine Triphosphate) in XLA patients compared to the healthy subjects (Table 2). Here, UQCR11 is linked to Bruton-type agammaglobulinemia.