TGFB1 and Fuchs endothelial corneal dystrophy: Further studies are needed to elucidate whether TGF-β induces the UPR by recruiting other proteins, such as type 3 collagen, clusterin, TGFBI, and proteoglycans, which are known to accumulate in FECD, similar to fibronectin and type 1 collagen19, 31, 32.