ANGPTL8 and hepatocellular carcinoma: ANGPTL8 is a recently defined gene also called C19orf80, LOC55908, refeeding-induced fat and liver (RIFL), TD26, hepatocellular carcinoma-associated gene, lipasin, and betatrophin (Quagliarini et al. 2012; Ren et al. 2012; Zhang 2012).