At 1 day after stroke, Vcam1, Madcam1, and Cx3cl1 showed upregulation (Fig. 1a, Vcam1, Madcam1, and Cx3cl1), and this change of Cx3cl1 expression remained 2 days later (Fig. 1a, Cx3cl1). The gene discussed is VCAM1; the disease is stroke disorder.