The results demonstrated that age (HR = 1.075, P < 0.001), WHO grade (HR = 9.560, P < 0.001), CCDC109B expression (HR = 1.861, P < 0.001), and mutation status of isocitrate dehydrogenase 1 (IDH1, HR = 0.244, P < 0.001), were all prognostic indicators for glioma patients (Table 2). The gene discussed is IDH1; the disease is central nervous system cancer.