A significant interaction between obesity and rs3826795 in relation with ALT was found (Pinter = 0.042), with rs3826795 G-allele number elevating ALT significantly only in obese children (β’ = 0.075, P = 0.037), but not in non-obese children (β’ = −0.009, P = 0.741). Here, GPT is linked to obesity due to melanocortin 4 receptor deficiency.