Another independent study reported that IL-17B bound to its receptor, IL-17RB, and then induced CCL20/CXCL1/IL-8/TFF1 activation, an event that subsequently rendered noticeable tumor-promoting effects such as the invasion of cancer cells, recruitment of macrophage and endothelial cells at primary sites, as well as resistance of treatments at the distant organs [38]. Here, IL17B is linked to neoplasm.