Of the 78 different inflammation- and metabolic-related markers assessed, 16 were associated with diabetes at P <0.05, including glucose transport and signaling pathway proteins (insulin, GIP, PP, glucagon, amylin, C-peptide), cytokines and cytokine receptors (sIL-6R, sTNFR1, STNFR2, and sIL-RII), and chemokines (CCL21, CCL20, CXCL11, CCL19, CXCL10, and CXCL6). This evidence concerns the gene INS and diabetes mellitus.