Because oxidative stress in lung tissue has been also considered to be important contributors to the pathogenesis of ALI [61], in this study, we have used lung tissues gene expression in hypoxia inducible factor-1-alpha (HIF-1α), heme oxygenase-1 (HO-1), glutathion peroxidase-1 (GPx-1), oxidative-stress responsive-1 (OXSR-1) as indicators to explore the potential oxidative stress role in brain death-induced lung injury in our model. This evidence concerns the gene HIF1A and acute respiratory distress syndrome.