Examples include microcoria in patients with laminin beta 2 (LAMB2) [20] mutations, coloboma in patients with paired box gene 2 (PAX2) [21] mutations, Denys–Drash syndrome (pseudohermaphroditism and Wilms tumor) or Frasier syndrome (streak gonads and pseudohermaphroditism) in patients with WT1 mutations [22], and nail–patella syndrome in individuals with LMX1B mutations [23]. This evidence concerns the gene WT1 and Nephroblastoma.