Platelet-derived microparticles (PMPs) play a role in tumor growth and invasiveness (at least in part by stimulation of MMP-2 production), and angiogenesis [by releasing vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)], as well as induce metastasis [58]. Here, FGF2 is linked to neoplasm.