CD4 and infection: Providing a basic science overview of the CD4+ T cell reservoir, he discussed: (1) the size and stability of the reservoir, (2) T cell subsets that comprise the reservoir, (3) the source of virus production, (4) the source of viral persistence, (5) the timing of reservoir establishment, and (6) current thoughts about macrophages as a reservoir, and prevention of infection and latency reversal in this population [6, , , –10].