CCL2 and tuberculosis: Another study has suggested the association of CCL2 with the pathogenesis of TB, by showing that the 6 kDa early secretory antigenic target (ESAT-6) of Mtb-induced CCL2 production in mouse bone marrow-derived macrophages and that the inhibition of p38 enhanced ESAT-6-induced CCL2 production (Ma et al., 2016).