Labeled RBCs from either wild-type, Ank-1(MRI96570/+), or Ank-1(MRI95845/MRI95845) mice were injected into infected wild-type mice of 1–10% parasitemia during late schizogony stage, and the parasitemia of each genotype was monitored over 36–40 hr to indicate relative invasion rates. Here, ANK1 is linked to parasitic infectious disease.