ANK1 and parasitic infectious disease: As shown in Figure 4D, the Ank-1(MRI96570/+) mice exhibited no significant reduction in RBC numbers, whereas Ank-1(MRI95845/MRI95845) mice were found to have a significantly shorter half-life of ∼6 d, which did not correlate with the parasitemia curve (Figure S4C in File S1).