As shown in Figure 2A, Ank-1(MRI96570/+) and Ank-1(MRI95845/+) mice showed significant reduction in peak parasitemia of ∼15–20%, while Ank-1(MRI95845/MRI95845) mice showed ∼30% reduction in peak parasitemia compared to wild type. Here, ANK1 is linked to parasitic infectious disease.