In particular, TFs previously implicated in PCa are hubs in our network: ERG, ETV1, ETV4, NR3C1, NKX3-1, ETV3, NRF1, TP53, STAT3, ETV5, MYC, and ETV6 [3, 4, 6, 9, 66]. This evidence concerns the gene STAT3 and posterior cortical atrophy.