For single TAAb in the diagnosis of early -stage lung cancer, there were 10 specific TAAbs (including CP, p53, TLP, Nectin-4, DKK1 and Survivin) originating from 10 articles for the analysis, with the sensitivities ranged from 24.1% to 100%, the specificities ranged from 24.1% to 97.7% and the accuracy ranging from 58.7 to 92.1% (mean 73.4, median 75.8) (Table 1). Here, NECTIN4 is linked to lung cancer.