As reported in Fig 2, which shows the distribution of specific and overlapping genes carrying rare variants identified in this study, among the three cardiomyopathic phenotypes, we detected five genes (DMD, OBSCN, SYNE1, TNNC1, VCL) carrying rare variants in the three phenotypes, six genes (AKAP9, CACNA1C, CHRM2, DLG1, MYO6, PSEN2) carrying rare variants in HCM and DCM, and one gene (TRPM4) carrying rare variants in ARVC and DCM. The gene discussed is SYNE1; the disease is Arrhythmogenic right ventricular dysplasia.