We next examined expression of these 94 genes in patients with EC using the cancer genome atlas.17 Of these 94 genes, 14 genes (NQO1, SLPI, GJB2, DNAJC15, S100A8, PLEKHS1, ESPN, RSPH1, KRT5, FOXJ1, IFI27, IFI6, LGR5 and MUC16) were significantly altered in tumour as compared to nontumour endometrial specimens (Figure S1). The gene discussed is RSPH1; the disease is cancer.