NQO1 has an established role in the endometrium.26NQO1 encodes NAD(P)H:quinone oxidoreductase 1 in detoxification pathways27, 28, 29 and has been reported to activate specific quinone‐derived pharmaceuticals including mitomycin C and apaziquone.30, 31 NQO1 also acts to protect the p53 tumour suppressor protein, and many other proteins involved in proliferation from proteasomal degradation.32 Interestingly, missense variants in NQO1 are implicated in many cancer types33, 34, 35 and more recently, increased NQO1 expression is associated with poor prognosis in ovarian36 and lung37 cancers. The gene discussed is NQO1; the disease is cancer.