Furthermore, STING agonists did not show any cytotoxic effects against murine cancer cell lines, including B16F10 melanoma, SCCFVII upper aero-digestive squamous cell carcinoma (Fu et al. 2015), CT26 colon carcinoma (Li et al. 2016), Hepa 1-6 hepatoma, LL/2 Lewis lung cancer (Tang et al. 2016), or human HSC-3 and Scc-4 tongue squamous cell carcinomas (Liang et al. 2015). This evidence concerns the gene STING1 and melanoma.