In cerulein-induced pancreatitis, reactive oxygen species are produced, resulting in accumulation of destructive oxygen and conducting leukocyte and prostaglandin synthesis; So, it is reasonable that any active compound which is able to scavenge free radicals and suppress NFκB generation, diminishes the inflammatory response, and eventually improve AP (Kim, 2008 ▶). This evidence concerns the gene NFKB1 and alkaline phosphatase measurement.