Despite the uncertainty of the underlying mechanism of the entero‐protective effects of lactadherin, a growing body of literature supports the notion that lactadherin could be used as an entero‐protective agent against colitis, sepsis, LPS‐induced inflammation, ischemia and similar (Ajakaiye, Jacob, Wu, & Yang, 2012; Aziz, Jacob, Matsuda, & Wu, 2011; Cui, Miksa, Wu, & Komura, 2010; Matsuda, Jacob, Wu, & Zhou, 2011; Shah, Wu, Jacob, & Molmenti, 2012). This evidence concerns the gene MFGE8 and Sepsis.