TNNI3 and acute coronary syndrome: In contrast to the setting of acute coronary syndrome, where hs-cTnI and hs-cTnT are strongly correlated13 and are considered diagnostically interchangeable18, recent data suggest a much lower correlation under non-acute conditions such as atrium fibrillation20, stable coronary artery disease19, and chronic kidney disease21 (see Supplementary Table S8).