The network contained 22 cancer-related target genes; FGF14, PAX3, DLX5, DLX6, MYT1, HAND2, GATA4, OLIG2, NKX6-1, PAX4, CA10, BARRHL2, SST, ONECUT1 and ONECUT3 differentially regulated by H3K9ac and RUNX1, BRD2, JUNB, RBBP6, TET2, MEF2D and TXNIP by H3K27me3. Here, HAND2 is linked to cancer.