GPT and Hepatic fibrosis: The extent of liver fibrosis in lentivirus-infected mice was determined by H&E staining, Sirius red staining, TUNEL staining, IHC and western blot for α-SMA and collagen1 (Supplementary Fig. 10a, b), the hepatic hydroxyproline content (Supplementary Fig. 10c) and the serum level of ALT and AST (Supplementary Table 2).