As shown in the heatmap in Fig. 4A, infection lead to an upregulation in core components of the inflammasome including the putative NLRC3 ortholog (wu:fb15h11), caspase b and il1β, as well as transcription factors previously shown to regulate inflammasome components and other known mediators of inflammasome activation or downstream effectors (Fig. 4A). The gene discussed is NLRC3; the disease is infection.