SUN1 and HIV-1 infection: In contrast, fusing the first 130 amino acids of SUN1 (N-terminal domain [NTD]) to the amino terminus of Fv1n (HASUN1NTD-Fv1n) was sufficient to reduce HIV-1 infection (Fig. 8B), though the extent of inhibition did not reach the levels observed with HASUN1, most likely due to lower expression levels (Fig. 8A).