An analysis of CD10 expression indicated heterogeneous moderate staining in the main tumor lesion and homogeneous intense staining in the tumor emboli (Fig. 4c) The tumor cells were negative for all of the other markers investigated (pan-keratin AE1-AE3, hormone receptors, alpha-inhibin, calretinin, Melan A, WT1). Here, CALB2 is linked to neoplasm.