TG and hypothyroidism: Musculoskeletal symptoms and signs are common in patients with thyroid dysfunctions[1] because the skeletal muscle is a major target of thyroid hormone (TH).[2] Hyperthyroidism mainly leads to symptoms like muscle weakness and wasting without creatine kinase (CK) elevation, whereas hypothyroidism causes myalgia and cramping with remarkable CK elevation, suggesting the presence of myopathies.[1,3,4]