SPMIP8 and infection: The resulting tepP::bla (ΔtepP) strain behaved like the CTL2-M062G1 tepP nonsense mutant in that it failed to induce the expression of interferon-induced peptides with the tetratricopeptide repeat (IFIT) genes (Fig. 2B) that are typically activated during the early stages of infection (6) and blocked the tyrosine phosphorylation of a subset of host proteins (Fig. 2C) (6).