Furthermore, intensity scoring of the immunohistochemical staining (15) on a scale of negative (0), weak (1), medium (2), and strong (3) revealed higher cumulative scores of MMS glioblastoma in the mesenchymal glioblastoma tumors as compared to the proneural subtype (ANG1, 2.9 vs 0.9; ANG2, 3.0 vs 1.2; VEGF-A, 2.3 vs 0.3; and VEGF-B, 2.7 vs 0.6) (Figure 5B). This evidence concerns the gene ANGPT2 and glioblastoma.