To investigate potential alterations of mitochondrial metabolism in GC, we carried out immunohistochemical staining of the mitochondrial outer membrane protein porin (a marker of mitochondrial mass) as well as all five OXPHOS complexes in tumor samples from 40 patients and compared the staining intensities with those of adjacent normal mucosal columnar epithelial tissues (Figures 1, –3; Supplementary Figure 1; Supplementary Tables 4 and 5). The gene discussed is VDAC1; the disease is neoplasm.