CD44 and infection: A previous work from our group demonstrated that following infection, splenic CD8+ T cells from T. cruzi-infected mice treated with recombinant Tc-aTS were positive for both activation marker CD44, as well as for Maackia amurensis (MAA), a lectin specific for α2-3 SIA, suggesting that Tc-aTS resialylates cell surface glycoconjugates of activated CD8+ T cells (Yamamoto et al., 1997; Freire-de-Lima et al., 2010).