ERCC1 and coronary artery disorder: After adjusting for covariates, ANCOVA models showed that ERCC1 mRNA expression (1.74 ± 0.36 vs 1.53 ± 0.59, P = 0.001) were higher in CAD patients than controls and then a significant association was found between variant genotypes (CT + TT) and decreased ERCC1 mRNA expression in CAD patients (P = 0.033) but not in controls (P = 0.488) (Fig. 3).