While Tsuata et al[77] and Capuzzo et al[78]reported that the IGF1R expression did not represent a prognostic factor in resected NSCLC patients, other research groups[79–81] have either found a negative prognostic significance of high IGF1R expression or IGF1R GCNC.[82] However, future results of stratified treatment-trials among NSCLC patients will be needed to fortify these results. The gene discussed is IGF1R; the disease is non-small cell lung carcinoma.