IGF1 and non-small cell lung carcinoma: However, the polysomy of chromosome 7 emerged as a highly specific (p = 0.002) negative prognosticator for all patients.IGF1Rgene copy number was a highly negative prognostic marker for all NSCLC patients (p = 0.037), but was even more significant in males (p = 0.015) than in females (p = 0.021).Finally, a high IGF-1 expression showed a trend as a negative prognostic marker in males (p = 0.053) but not for the whole cohort population.