Given the marked elevation of transcripts for proinflammatory cytokines (IFN-γ and TNF-α) and T-cell recruiting signals (CXCL9 and CXCR3) in infected brains (Figs 1 and 2), we decided to focus on lethal infection, especially vascular/cellular activation and leukocyte recruitment. The gene discussed is CXCL9; the disease is infection.