One of the most remarkable features ofPRRSV infection is the failure to elicit the expression of inflammatory cytokines inthe lungs of pigs, particularly type I interferons, interleukin-1 (IL-1) and tumournecrosis factor alpha (TNF-α), which are important in antiviral responses.Whether this phenomenon is related to the function of Siglec-10 needs to beidentified [41, 42]. This evidence concerns the gene TNF and infection.