The occurrence of IgE to bacterial antigens was also observed in atopic dermatitis (AD) patients as early as 1981.8, 9, 10, 11, 12 Anti‐Staphylococcal IgE has been found in atopic dermatitis patients with or without cutaneous Staphylococcal infection,8, 9, 10, 11, 12 and IgE reactivity against various antigens such as Staphylococcal exotoxins13 and S. aureus fibronectin‐binding protein14 has been reported. Here, IGHE is linked to Alzheimer disease.