Several studies have observed IgE sensitization to bacterial antigens in children suffering from asthma.2, 3, 4 In particular, IgE antibodies directed against enterotoxins from Staphylococcus aureus (S. aureus) were found to be associated with severe forms of asthma5, 6 and recently Staphylococcal serine protease‐like proteins were suggested as pacemakers of allergic airway reactions to S. aureus. The gene discussed is IGHE; the disease is asthma.