Czyzyk‐Krzeska and Trzebski16 and Malpas et al showed that the activity of renal nerves increased during hypoxia, which is likely to induce renin secretion.16,17 Regarding increased renin secretion during atherosclerosis, it should be mentioned that the relationship between RAS and atherosclerosis has been revealed in many publications. The gene discussed is REN; the disease is atherosclerosis.