EGFR and neoplasm: A majority of studies applying morphological criteria have described their tissue as EGFR positive when staining occurs in the cell membrane [9, 18-21, 23, 26, 27, 30-36], while others have included cytoplasmic staining or mixed cytoplasmic/membranous staining [15, 24, 28, 29] or have specifically evaluated staining in the tumor stroma [37].