These data evidence the inverse correlation between the expression of miR-146a [21] and D6/ACKR2 receptor (Figure 2) in normal and neoplastic thyroids, confirming that D6/ACKR2 was down-regulated by miR-146a also in human specimens, and suggest that D6/ACKR2 expression is lost along with the de-differentiated state of thyroid carcinomas. The gene discussed is ACKR2; the disease is thyroid gland carcinoma.