In MG, interleukin-6 (IL-6) produced by different cell types within the tumor microenvironments (including reactive stromal cells, tumor cells, and macrophages) is believed to stimulate the proliferation of plasma cells and play a critical role in the promotion of angiogenesis both directly and indirectly through enhanced VEGF secretion [40–43]. The gene discussed is VEGFA; the disease is neoplasm.