There were significantly more CD45+ immune cells around (T2D: 5.68 ± 0.52, ND: 2.72 ± 0.28 cells per islet; p = < 0.0001; Fig. 1a,b) and within (T2D: 4.10 ± 0.70, ND: 1.44 ± 0.24 cells per islet; p = 0.0003; Fig. 1a,c) pancreatic islets of T2D subjects. This evidence concerns the gene PTPRC and type 2 diabetes mellitus.