Of the 40 genes with the highest gene importance scores, 12 genes, PSMG1, PTGER4, CPEB4, EGR2, RFX3, IL1R1, LRRK2, GPR183, ZMIZ1, ELMO1, TNFSF11, SATB2 are associated with other autoimmune diseases than SLE according to the GWAS catalog (Table 1). This evidence concerns the gene IL1R1 and autoimmune disease.