SLC2A5 and breast carcinoma: Also the IC50 for MSNBA inhibition of fructose uptake by hxt0GLUT5 is comparable to that determined in human breast carcinoma MCF-7 cells and ~10-fold lower than that determined in GLUT5 proteoliposomes20, making the yeast system superior to GLUT5 proteoliposomes and comparable to human cell lines systems in assessing GLUT5 inhibition.