Association of β-SQDG18 to hgp10025–33 peptide induced in vivo expansion of both memory lymphocytes and APCs, as indicated by the increase in the percentage of CD8+CD44 high T lymphocytes and CD3-CD19-CD80+ cells among splenocytes in immunized mice in comparison with unvaccinated tumour-challenged animals (Fig. 4E and F). This evidence concerns the gene CD44 and neoplasm.