To determine whether genetic variants near CFB are associated with metabolic and cardiovascular disorders relevant to MetS (Table S3), we mined the NHGRI GWAS catalog (National Human Genome Research Institute) and located 18 single-nucleotide polymorphisms (SNPs) associated with cardiometabolic traits ≤1 Mb from CFB (Figure 5; Table S6). The gene discussed is CFB; the disease is cardiovascular disorder.